The Fermi Paradox

Enrico Fermi was a great scientist, and I want to read a biography if I can find one.
The latest Hubble Deep Field picture: http://hubblesite.org/newscenter/newsdesk/archive/releases/2004/07/
shows a close view of one tiny spot of sky where there seemed to be nothing.
It is filled with galaxies, and each glaxy has billions of stars. Somewhere there should be some life like us. There is an equation describing the liklihood of life outside Earth, the Drake equation:
http://www.homoexcelsior.com/omega.db/datum/extraterrestrial_life/drake's_equation/8525
So Fermi's question was simply, "So where are they?"
I wonder if the lack of alien life could be a warning that we are headed for disaster.